Archive

QUANTIFICATION OF LUPEOL: AN ACTIVE MARKER FROM KANCHNAR PRODUCTS BY HPTLC

Print

1Awad Jayesh S. ,2 Londhe Rutuja P. , 3Utteker Pranav S. , 4Damle Mrinalini C.

DOI : http://dx.doi.org/10.47191/ijahm/v13i2.06

Download Pdf

Abstract:

Kanchnar (Bauhinia variegate) is tree growing in different parts of India. It is known to have analgesic and anti-inflammatory properties.  Kanchnar's anti-inflammatory and antioxidant characteristics encourage the growth of new skin cells, which aids in wound healing.  Kanchnar is available in the market as a variety of dosage forms, including churna, kashay, ointment, pills, topical gel etc. Prior to administration, standardization of herbal products is crucial for ensuring their quality. In light of this, the current study involved quantification of  lupeol, an active marker found in kanchnar (Bauhinia variegate) bark and its two commercially available formulations. Bark extraction was done using maceration. The mobile phase was optimized and locating agent was used to visualize lupeol.

Keywords- Bauhinia variegate, standardization, HPTLC, Lupeol.

REERENCES: 

  1. Sachin, Dr.Naresh Kumar Garg, Dr.Omprakash Sharma. A review article on: Kanchnara (Bauhinia variegate Linn. World Journal Of  Pharmaceutical and Medical Research,2021,7(6), 143-147.
  2. Vikas Nariyal, Priyanka Sharma. Kanchnar(Bauhinia variegata) as a medicinal herb: A systematic review. International Journal of Advanced Research (IJAR), 2017, 5(9), 587-591.
  3. Pooja Singh, R.C. Tiwari, RakeshBhutiani, Vasu Singh. Kanchnar(Bauhinia Variegata Linn.)as a thyroid Gland protecting drug. Ayushdhara, 2021,8(3):3349-3353.
  4. Anitasingh, P. Bhardwaaj, C. Varshneya, R.S. telang. Anthelmintic activity of leaves of Bauhinia variegate. Indian Vet. J., August,2005; 82:855-857.
  5. K.Kaashefah Jinaan, S.Udhayavani, S.K.Bibi Ayesha. Pharmacological activity of Bauhinia variegate and Bauhinia purpurae. World Journal of  Pharmaceutical Research, 2021,10(1): 203-218.
  6. Arti Gupta, Navin R Sheth,SoniaPandey, Jitendra Singh Yadhav, Determination of Quercetin a Biomarker in Hepatoprotective Polyherbal Formulation High Performance Thin Layer Chromatography. J Chromtogrep Tech, 2015 , 6, 285.
  7. ICH Q2 (R1): Validation of Analytical Procedures: Text and Methodology (2005)
  8. Gayathri Gunalan, A. Saraswathy, K. Vijayalakshmi. HPTLC fingerprint profile of Bauhinia variegateleaves.Asian Pacific Journal of Tropical Disease, 2012, 2(1), S21-S25.
Category: Volume 13 Issue 02 (March-April 2023)